Investigación

¿Qué dice la investigación?

Los científicos han investigado ampliamente el beta-glucano de cebada como una forma de bajar el colesterol con alimentos naturales. Encontraron que, cuando las personas toman al menos 3 gramos de fibra de beta-glucano al día durante 4 a 12 semanas, su colesterol de lipoproteínas de baja densidad (colesterol LDL) se reduce. Además, el beta-glucano de cebada es reconocido por la FDA, Health Canada y la Autoridad Europea de Seguridad Alimentaria. Para saber cómo Cerabeta ayuda a bajar su colesterol de forma natural, haga clic aquí.

 
Investigación sobre el beta-glucano de cebada

AbuMweis , S S, et al. “β-Glucan from Barley and Its Lipid-Lowering Capacity: a Meta-Analysis of Randomized, Controlled Trials.” European Journal of Clinical Nutrition, U.S. National Library of Medicine, Dec. 2010, pubmed.ncbi.nlm.nih.gov/20924392/.  

Behall , Kay M, et al. “Diets Containing Barley Significantly Reduce Lipids in Mildly Hypercholesterolemic Men and Women.” The American Journal of Clinical Nutrition, U.S. National Library of Medicine, Nov. 2004, pubmed.ncbi.nlm.nih.gov/15531664/.  

Behall, Kay M, et al. “Lipids Significantly Reduced by Diets Containing Barley in Moderately Hypercholesterolemic Men.” Journal of the American College of Nutrition, U.S. National Library of Medicine, Feb. 2004, pubmed.ncbi.nlm.nih.gov/14963054/.  

Bourdon, I, et al. “Postprandial Lipid, Glucose, Insulin, and Cholecystokinin Responses in Men Fed Barley Pasta Enriched with Beta-Glucan.” The American Journal of Clinical Nutrition, U.S. National Library of Medicine, Jan. 1999, pubmed.ncbi.nlm.nih.gov/9925123/.  

Keenan JM;M;T;Knutson N;Kolberg L;Curry L;, Joseph, et al. “The Effects of Concentrated Barley Beta-Glucan on Blood Lipids in a Population of Hypercholesterolaemic Men and Women.” The British Journal of Nutrition, U.S. National Library of Medicine, June 2007, pubmed.ncbi.nlm.nih.gov/17445284/. 

Li, Jue, et al. “Effects of Barley Intake on Glucose Tolerance, Lipid Metabolism, and Bowel Function in Women.” Nutrition (Burbank, Los Angeles County, Calif.), U.S. National Library of Medicine, 2003, pubmed.ncbi.nlm.nih.gov/14624940/. 

McIntosh , G H, et al. “Barley and Wheat Foods: Influence on Plasma Cholesterol Concentrations in Hypercholesterolemic Men.” The American Journal of Clinical Nutrition, U.S. National Library of Medicine, May 1991, pubmed.ncbi.nlm.nih.gov/1850576/.  

Narain, J P, et al. “Metabolic Responses to a Four Week Barley Supplement.” Taylor & Francis, July 2009, https://www.tandfonline.com/doi/abs/10.3109/09637489209027531?journalCode=iijf20  
Newman, R.K., et al. “Hypocholesterolemic Effect of Barley Foods on Healthy Men.” AGRIS, 1 Jan. 1989, agris.fao.org/agris-search/search.do?recordID=US8922720.  

Rondanelli, M, et al. “Beta-Glucan- or Rice Bran-Enriched Foods: a Comparative Crossover Clinical Trial on Lipidic Pattern in Mildly Hypercholesterolemic Men.” European Journal of Clinical Nutrition, U.S. National Library of Medicine, July 2011, pubmed.ncbi.nlm.nih.gov/21505506/. 

Shimizu, Chikako, et al. “Effect of High Beta-Glucan Barley on Serum Cholesterol Concentrations and Visceral Fat Area in Japanese Men--a Randomized, Double-Blinded, Placebo-Controlled Trial.” Plant Foods for Human Nutrition (Dordrecht, Netherlands), U.S. National Library of Medicine, Dec. 2007, pubmed.ncbi.nlm.nih.gov/18074229/.   

Sima, Petr, et al. “β-Glucans and Cholesterol (Review).” International Journal of Molecular Medicine, D.A. Spandidos, Apr. 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810204/  
Talati, Ripple, et al. “The Effects of Barley-Derived Soluble Fiber on Serum Lipids.” Annals of Family Medicine, U.S. National Library of Medicine, 2009, pubmed.ncbi.nlm.nih.gov/19273871/.

Investigación sobre Cerabeta y la salud intestinal

El beta-glucano de cebada, presente en la fibra de beta-glucano Cerabeta, es una fuente de fibra dietética que ayuda a apoyar y mantener un sistema digestivo saludable. El beta-glucano de cebada ha mostrado efectos in vivo sobre la microbiota intestinal, con un aumento de los ácidos grasos de cadena corta (AGCC) y de poblaciones de bacterias beneficiosas como las bacterias del ácido láctico (BAL). Las BAL tienen posibles beneficios para la salud, como el control de infecciones intestinales y una mejor digestión de la lactosa. En cuanto a la saciedad, la investigación ha demostrado que el consumo de beta-glucano de cebada aumenta la viscosidad del contenido digestivo. Una mayor viscosidad retrasa el vaciado gástrico y hace más lenta la metabolización y absorción de los nutrientes, en especial la glucosa, debido a una menor actividad enzimática y absorción en la mucosa, lo que produce una sensación temprana de saciedad.

Arena M, Caggianiello G,Fiocco D, Russo P,Torelli M, Spano G, Capozz V. (2014). Barley β-Glucans-Containing Food Enhances Probiotic Performances of Beneficial Bacteria. International Journal of Molecular Sciences. 15(2): 3025–3039. https://www.ncbi.nlm.nih.gov/pubmed/24562330

Carlson J, Erickson J, Hess J, Gould T, Slavin J. (2017). Prebiotic Dietary Fiber and Gut Health: Comparing the in Vitro Fermentations of Beta-Glucan, Inulin and Xylooligosaccharide. Nutrients, 9(12): 1361. https://www.ncbi.nlm.nih.gov/pubmed/29244718

De Angelis M, Montemurno E, Vannini L, Cosola C, Cavallo N, Gozzi G, Maranzano V, Di Cagno R, Gobbetti M, Gesualdo L. (2015). Effect of whole-grain barley on human fecal microbiota and metabolome. Applied and Environmental Microbiology, 7945-7956. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616929/

Gilliland S. Health and nutritional benefits from lactic acid bacteria. (1990). FEMS Microbiology Letters, 87(1–2): 175-188. https://doi.org/10.1111/j.1574-6968.1990.tb04887.x
Health Canada. Monograph Betaglucan. (2019). https://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq?atid=beta.glucane&lang=eng

Wang Y, Ames N, Li S, Jones P, and Khafipour E. (2014). High molecular weight barley β-glucan supports bacterial populations beneficial for gut health. The faseb Journal, 28:1 supplement. https://doi.org/10.1096/fasebj.28.1_supplement.647.45

El Khoury D, Cuda C, Luhovyy B, Anderson G. (2011). Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome. Journal of Nutrition and Metabolism, Vol 2012, 28p. https://www.hindawi.com/journals/jnme/2012/851362/

Schroeder N, Gallaher DD, Arndt EA, Marquart L. (2009). Influence of whole grain barley, whole grain wheat, and refined rice-based foods on short-term satiety and energy intake. Appetite. 53(3):363–369. https://www.ncbi.nlm.nih.gov/pubmed/19643157

Vitaglione P, Lumaga RB, Montagnese C, Messia MC, Marconi E, Scalfi L. (2010). Satiating effect of a barley beta-glucan-enriched snack. Journal of the American College of Nutrition, 29(2):113–121. https://www.tandfonline.com/doi/abs/10.1080/07315724.2010.10719824

Vitaglione P, Lumaga RB, Stanzione A, Scalfi L, Fogliano V. (2009). β-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. Appetite, 53(3):338–344. https://www.ncbi.nlm.nih.gov/pubmed/19631705